Fig. 7.

Loss of Cdk9 function expands both the premigratory and migratory NC populations, and suppresses loss of melanophore formation in aln/paf1 mutants. (A-D) Lateral views of 48 hpf wild-type (A), aln^z24 mutant (B), cdk9^z26 mutant (C) or aln^z24; cdk9^z26 double mutant embryos (D). (E-H) NC expression of crestin (E,F) and sox10 (G,H) in 26 hpf wild-type and cdk9^z26 mutant embryos. Arrow in C indicates an increase in the number of melanophores in the head of cdk9^z26 mutant embryos. Insets in E and F are cross-sections through the trunk of crestin-expressing embryos. Arrows indicate migrating NC and arrowheads indicate premigratory NC.