TABLE 1.

Cellular gene transcripts categorized using a threshold of a 4-fold change based on the pattern of response to either CTCF or Rad21 KD^a

Category	Response		No. of genes
	CTCF KD	Rad21 KD
1	↑↑↑	↑↑↑	145
2	↑↑↑	−	287
3	↑↑↑	↓↓↓	2
4	−	↑↑↑	208
5	−	−	23,921
6	−	↓↓↓	124
7	↓↓↓	↑↑↑	0
8	↓↓↓	−	209
9	↓↓↓	↓↓↓	99
Total			24,995

^a↑↑↑, gene expression was upregulated; −, gene expression did not change; ↓↓↓, gene expression was downregulated.