TABLE 1.
Curated list of factors altered by the presence of HPV16 cells versus HFKs
| Protein | Ratio | P value |
|---|---|---|
| P73 (phospho-Tyr99) | 8.29 | 0.0004 |
| Tau (Ab-231) | 8.12 | 0.0442 |
| PAK2 (Ab-192) | 6.72 | 0.0105 |
| MEK1 (Ab-217) | 5.41 | 0.0488 |
| Rel (phospho-Ser503) | 4.95 | 0.0192 |
| Fos (Ab-232) | 4.43 | 0.0132 |
| Chk1 (phospho-Ser301) | 4.14 | 0.0138 |
| MEK1 (phospho-Thr291) | 4.05 | 0.0053 |
| MKK7/MAP2K7 (Ab-271) | 4.03 | 0.0007 |
| AKT1 (phospho-Ser473) | 3.90 | 0.0238 |
| BCL-6 (Ab-333) | 3.84 | 0.0064 |
| IκB-alpha (phospho-Tyr305) | 3.83 | 0.0476 |
| MEK1 (phospho-Ser298) | 3.75 | 0.0033 |
| MDM4 (phospho-Ser367) | 3.71 | 0.0057 |
| Integrin beta-3 (Ab-773) | 3.64 | 0.0021 |
| p44/42 MAPK (Ab-204) | 3.58 | 0.0398 |
| Mnk1 (Ab-385) | 3.47 | 0.0049 |
| MEK2 (phospho-Thr394) | 3.46 | 0.0273 |
| GSK3 beta (phospho-Ser9) | 3.46 | 0.0455 |
| Chk1 (phospho-Ser286) | 3.36 | 0.0373 |
| NF-κB–p65 (Ab-311) | 3.31 | 0.0319 |
| AKT1 (phospho-Thr308) | 3.27 | 0.0114 |
| FGFR1 (phospho-Tyr766) | 3.24 | 0.0151 |
| STAT1 (phospho-Ser727) | 3.23 | 0.0045 |
| IκB-beta (phospho-Ser23) | 3.22 | 0.0450 |
| MAP3K7/TAK1 (Ab-439) | 3.12 | 0.0354 |
| JunD (Ab-255) | 3.11 | 0.0142 |
| HER2 (phospho-Thr686) | 3.10 | 0.0256 |
| Fyn (phospho-Tyr530) | 3.09 | 0.0214 |
| IGF2R (Ab-2409) | 3.05 | 0.0215 |
| CREB (Ab-129) | 3.00 | 0.0367 |
| MKK4/SEK1 (phospho-Thr261) | 2.95 | 0.0176 |
| AKT1 (phospho-Tyr474) | 2.94 | 0.0479 |
| MKK4/SEK1 (phospho-Ser257) | 2.72 | 0.0027 |
| p44/42 MAPK (Ab-202) | 2.72 | 0.0037 |
| IGF1R (phospho-Tyr1161) | 2.60 | 0.0283 |
| MEK1 (phospho-Ser221) | 2.54 | 0.0496 |
| MEF2A (phospho-Ser408) | 2.54 | 0.0190 |
| MKK3/MAP2K3 (Ab-189) | 2.53 | 0.0240 |
| Chk1 (Ab-345) | 2.50 | 0.0468 |
| c-Jun (Ab-63) | 2.47 | 0.0284 |
| Elk1 (Ab-383) | 2.43 | 0.0202 |
| Dok-2 (Ab-299) | 2.42 | 0.0036 |
| EGFR (Ab-1197) | 2.30 | 0.0412 |
| c-Jun (Ab-170) | 2.17 | 0.0416 |
| c-Jun (phospho-Thr91) | 2.15 | 0.0044 |
| 4E-BP1 (phospho-Ser65) | 2.12 | 0.0034 |
| FAK (Ab-861) | 2.12 | 0.0197 |
| EGFR (phospho-Tyr1016) | 2.02 | 0.0280 |
| AKT1 (phospho-Ser124) | 2.02 | 0.0308 |
| Src (phospho-Ser75) | 2.01 | 0.0084 |
| Rel (Ab-503) | −1.99 | 0.0109 |
| c-Jun (phospho-Thr93) | −2.04 | 0.0252 |
| STAT1 (phospho-Tyr701) | −2.22 | 0.0467 |
| PDGFR beta (Ab-751) | −2.25 | 0.0242 |
| VAV1 (Ab-160) | −2.30 | 0.0112 |
| NF-κB–p100/p52 (phospho-Ser872) | −3.49 | 0.0394 |