TABLE 3.
Curated list of factors altered by the presence of E5 Stop versus HPV16 cells
| Protein | Ratio | P value |
|---|---|---|
| p38 MAPK (Ab-182) | 4.44 | 0.0245 |
| Src (Ab-418) | 3.73 | 0.0140 |
| STAT5A (Ab-780) | 3.47 | 0.0119 |
| p53 (Ab-18) | 3.42 | 0.0254 |
| CREB (phospho-Thr100) | 3.34 | 0.0161 |
| STAT6 (Ab-645) | 3.30 | 0.0478 |
| PECAM-1 (Ab-713) | 3.24 | 0.0454 |
| P90RSK (Ab-359/363) | 2.84 | 0.0258 |
| VEGFR2 (Ab-1214) | 2.81 | 0.0236 |
| STAT1 (phospho-Tyr701) | 2.75 | 0.0001 |
| Pyk2 (Ab-580) | 2.55 | 0.0406 |
| Smad3 (phospho-Ser213) | 2.52 | 0.0184 |
| PTEN (Ab-370) | 2.30 | 0.0255 |
| Rel (Ab-503) | 2.24 | 0.0046 |
| PI3-kinase p85-subunit alpha/gamma (Ab-467/199) | −2.03 | 0.0227 |
| Elk1 (Ab-389) | −2.03 | 0.0467 |
| PAK2 (Ab-192) | −2.05 | 0.0355 |
| Integrin beta-4 (phospho-Tyr1510) | −2.05 | 0.0060 |
| JunB (phospho-Ser79) | −2.06 | 0.0270 |
| AKT1 (phospho-Ser124) | −2.08 | 0.0291 |
| Tau (phospho-Thr212) | −2.09 | 0.0054 |
| FLT3 (phospho-Tyr599) | −2.12 | 0.0277 |
| AKT1 (phospho-Thr308) | −2.14 | 0.0216 |
| TYK2 (Ab-1054) | −2.20 | 0.0118 |
| MEK1 (phospho-Ser298) | −2.21 | 0.0146 |
| FGFR1 (phospho-Tyr766) | −2.32 | 0.0288 |
| IGF1R (phospho-Tyr1161) | −2.37 | 0.0289 |
| EEF2 (phospho-Thr56) | −2.42 | 0.0180 |
| MEF2A (phospho-Ser408) | −2.45 | 0.0153 |
| MKK7/MAP2K7 (Ab-271) | −2.47 | 0.0011 |
| Elk1 (Ab-383) | −2.49 | 0.0168 |
| GSK3 alpha (Ab-21) | −2.53 | 0.0348 |
| p44/42 MAPK (Ab-202) | −2.55 | 0.0046 |
| MDM4 (phospho-Ser367) | −2.60 | 0.0081 |
| c-Jun (Ab-170) | −2.62 | 0.0232 |
| c-Jun (Ab-63) | −2.66 | 0.0243 |
| Cyclin E1 (phospho-Thr395) | −2.68 | 0.0030 |
| AKT1 (phospho-Ser473) | −2.68 | 0.0299 |
| MEK1 (Ab-221) | −2.80 | 0.0203 |
| JunD (Ab-255) | −2.81 | 0.0103 |
| FAK (Ab-397) | −2.83 | 0.0137 |
| eIF4G (phospho-Ser1108) | −2.85 | 0.0020 |
| MEK1 (phospho-Thr291) | −2.87 | 0.0105 |
| MEK1 (phospho-Ser221) | −2.89 | 0.0387 |
| MEK2 (phospho-Thr394) | −2.94 | 0.0289 |
| GSK3 alpha (phospho-Ser21) | −3.30 | 0.0223 |
| VEGFR2 (phospho-Tyr951) | −3.69 | 0.0011 |
| GSK3 beta (phospho-Ser9) | −3.89 | 0.0414 |
| Fos (Ab-232) | −3.91 | 0.0160 |
| P73 (phospho-Tyr99) | −4.94 | 0.0001 |
| Tau (Ab-231) | −6.42 | 0.0481 |