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Pathways affected in E5 Stop versus HPV16+ cells
| Regulation | E5 Stop vs HPV16 pathway | No. of genes from array | % of total array genes | P value | FDRa |
|---|---|---|---|---|---|
| Down | ErbB signaling | 16 | 25.0 | 2.40E−16 | 2.66E−13 |
| Down | VEGF signaling | 11 | 17.19 | 6.25E−11 | 7.55E−08 |
| Down | PI3K-Akt signaling | 19 | 29.69 | 2.56E−10 | 3.09E−07 |
| Down | MAPK signaling | 16 | 25 | 1.89E−09 | 2.28E−06 |
| Down | Ras signaling | 15 | 23.44 | 4.09E−09 | 4.94E−06 |
FDR, false-discovery rate.
