Table 1.
Simulation parameters for the 4 5-HT3A systems simulated with membranes composed of POPC, SDPC, and CHOL or POPC only
| System | No. POPC | No. SDPC | No. CHOL | No. of waters | No. of ions (Cl−/K+) | Time, μs |
| 5-HT3A-Apo | 126 | 126 | 108 | 43,395 | 138/163 | 20 |
| 5-HT3A-5mM | 126 | 126 | 108 | 48,528 | 150/170 | 15 |
| 5-HT3A-15mM | 126 | 126 | 108 | 48,994 | 153/163 | 15 |
| 5-HT3A-5mM-POPC | 250 | 0 | 0 | 41,552 | 132/152 | 15 |
Abbreviations: CHOL, cholesterol; POPC, 1-palmitoyl-2-oleoyl-SN-glycero-3-phosphocholine; SDPC, 1-stearoyl-2-docosahexaenoyl-sn-glyerco-3-phospho-choline.