Table 4.

Clinical outcomes of implantation potential according to type of oocytes

	RF(‐) oocytes		RF(+) oocytes		Crude difference					Adjusted difference
		95% CI		95% CI	Estimated regression coefficient	SE	COR	95% CI	P‐value	estimated regression coefficient	SE	aOR	95% CI	P‐value
No. of transferred embryos	339		99
Implantation rate	42.2% (143/339)	37.0‐47.5	24.2% (24/99)	16.9‐33.5	−0.824	0.259	0.44	0.26‐0.72	.001	−0.778	0.278	0.46	0.26‐0.78	.005
Implantation rate of high‐quality blastocyst transferred	46.1% (111/241)	39.9‐52.4	28.6% (18/63)	18.9‐40.7	−0.758	0.307	0.47	0.25‐0.84	.014	−0.688	0.341	0.50	0.25‐0.96	.043
Live birth rate	29.2% (99/339)	24.6‐34.3	19.2% (19/99)	12.6‐28.0	−0.552	0.282	0.58	0.32‐0.98	.050	−0.514	0.314	0.60	0.31‐1.08	.101
Live birth rate of high‐quality blastocyst transferred	33.6% (81/241)	27.9‐39.8	22.2% (14/63)	13.7‐33.9	−0.572	0.332	0.56	0.29‐1.06	.085	−0.523	0.378	0.59	0.27‐1.21	.166
aNeonatal abnormality rate	3.0% (3/99)	1.0‐8.5	0% (0/19)						.995
Pregnancy loss rate	30.8% (44/143)	23.8‐38.8	20.8%b (5/24)	9.2‐40.5	−0.524	0.534	0.59	0.19‐1.58	.327	−0.557	0.558	0.57	0.17‐1.59	.318
Pregnancy loss of high‐quality blastocyst transferred	27.0% (30/111)	19.6‐36.0	22.2% (4/18)	9.0‐45.2	−0.260	0.606	0.77	0.21‐2.35	.668	−0.277	0.619	0.76	0.19‐2.41	.655

Implantation rates, live birth rates, and pregnancy loss rates were analyzed using a mixed‐effects logistic regression model that contains terms for the presence of RFs (0/1), age, and high‐grade blastocyst development (0/1) as fixed effects and patient‐specific intercept as a random effect.

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio.

^aThe neonatal abnormalities found in the newborn babies were pulmonary valve stenosis, small for gestational age, and cleft palate.

^bOne stillbirth, occurring at 24 wk and 6 d, has been included in the pregnancy loss rate.