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. 2019 Dec 1;38(4):215–232.

Table 3.

A representation of exercise interventions done in FSHD. Number in parenthesis represents the article reference.

Exercise mode/N Duration Frequency Intensity Improved outcome
Cycling
N = 8

Control group
N = 7

(17)
12 weeks 5 days/week
35 min/session
65% VO2max VO2max, workload, and ADL
Cycling + post exercise protein-carbohydrate supplement
N = 18

Cycling + placebo supplement
N = 13

Control group
N = 10

(18)
12 weeks

12 months F/U
3 days/week
15 min/session week 1
20 min/session week 2

30 min/session from week 3
70% VO2max 6MWT, workload, fitness, and SF-36
Cycling
N = 20

Cognitive-behavioral therapy
N = 13

Usual care
N = 24

(19)
16 weeks 3 days/week (2 days at home and 1 day supervised)

38 min/session, including a 5 min warm up 30 min exercise 3 min cool down

Cognitive-behavioral therapy comprised of 6 modules:
Dysfunctional cognitions regarding fatigue, activity, pain, or other symptoms; fatigue catastrophizing (a cognitive process that involves negative outcome expectations from fatigue); dysregulation of sleep or activity; poor social support; and negative social interactions. Both aerobic exercise therapy and cognitive behavioral therapy were found to be superior to usual care in reducing fatigue
50-65% HRmax

12-14 RPE (Borg Scale)
Fatigue
Cycling
N = 8

Control group
N = 8

(20)
24 weeks 3 days/week
35 min/session
2 sessions at 60% max aerobic power
1 session interval training 40% and 80% max aerobic power
VO2max, 6MWT, and fatigue severity scale
Strength
N = 34

Control
N = 31

(21)
52 weeks 3 days/week 10 RM, 2 sets x 5-10 reps Dynamic and isometric strength:
Elbow flexion and ankle dorsal flexion
1RM, and dynamic elbow flexor strength
HIT:
Cycling
N = 6

UC
N = 7

Control group
N = 7

(22)
8 weeks supervised

8 weeks with unsupervised for all.
21 min/session, including an 8-min warm-up and two sets of
5-min HIT with 3-min break at very low intensity.

3 days/week
Each minute of HIT was performed at three
different work intensities: 30 s of easy pedaling (low
intensity), 20 s of hard work (middle high intensity), and
10 s of all-out, maximal intensity
VO2max and workload
NMES
N = 9

(23)
5 months 5 days/week
20 min/session
Rise time 1.5s; steady tetanic stimulation
time: 6s; fall time 1.5s
Pain, fatigue, shoulder flexion strength, knee extension strength, and 6MWT