Table 5.

A representation of exercise interventions done in McArdle disease. Number in parenthesis represents the article reference.

Exercise mode/N	Duration	Frequency	Intensity	Improved outcome
Cycling N = 8 (32)	14 weeks	Week 1-7: 4 days/week 30 min/session Week 8-14: 4 days/week 40 min/session	60-70% HRmax	Oxidative and work capacity
Electromagnetically braked cycling N = 7 (33)	12 weeks	4 days/week 60-90 min/session	65-70% of HRmax	Aerobic capacity and work load
Acute: Cycling (strictly monitored) N = 46 Control group N = 46 Chronic: Walking or cycling N = 9 (34)	Acute: 1 day Chronic: 8 months	1 day 5 days/week 60 min/session	1. Workload increased with 10 Watt/min until exhaustion, starting at 10 Watt 2. A 12-minute constant-load test at the power output reaching ventilatory threshold on a cycle The two tests were separated by a 10-minute active rest period (freewheel pedaling) 75 g sucrose beverage prior to test 60% of HRmax Complex carbs 1 hour before exercise and simple carbs during exercise	Aerobic capacity, peak power output, and ventilatory threshold
Strength N = 1 (35)	6 weeks	2 days/week Up to 60 min/session	65-70% of 1RM 10-minute warm-up consisting of 5 minutes of light-intensity dynamic exercise (on a cycle ergometer or rowing ergometer), followed by 5 minutes of mobilization exercisesand body weight exercises (eg, shoulder shrugs and rotations, arm elevations, changing squat stance, walkinglunges, push-ups on the wall). Benchpress with free weights, multipower squat, shoulder press, armcurls and elbow extensions with dumbbells, lateral pulldown, abdominal crunches, and low back extensions. 2-3 sets x 10-15 reps	Patient changed to a lower disease severity class