Table 1.
Single Administration | Multiple Administration | |||||
---|---|---|---|---|---|---|
Placebo | Adrenomedullin | Placebo | Adrenomedullin | |||
Low | Medium | High | High | |||
N | 6 | 6 | 6 | 6 | 6 | 6 |
Age, years | 23.2 ± 4.3 | 25.0 ± 3.9 | 24.7 ± 7.1 | 24.7 ± 7.0 | 26.2 ± 5.1 | 28.0 ± 6.0 |
BH, cm | 172.9 ± 3.2 | 175.8 ± 6.1 | 168.9 ± 6.0 | 170.9 ± 7.1 | 173.6 ± 4.8 | 169.8 ± 6.8 |
BW, kg | 63.7 ± 3.5 | 69.2 ± 7.2 | 60.7 ± 4.7 | 64.0 ± 7.0 | 67.8 ± 8.7 | 63.0 ± 7.7 |
SBP, mmHg | 122.2 ± 10.1 | 116.2 ± 11.2 | 117.3 ± 8.7 | 120.8 ± 6.7 | 121.3 ± 8.7 | 122.5 ± 7.8 |
DBP, mmHg | 70.7 ± 9.8 | 66.5 ± 6.3 | 72.2 ± 4.9 | 73.0 ± 6.7 | 71.3 ± 5.7 | 72.8 ± 3.9 |
PR, bpm | 60.8 ± 12.2 | 60.2 ± 8.4 | 63.7 ± 10.7 | 56.3 ± 7.3 | 60.2 ± 9.4 | 57.8 ± 9.2 |
Note: Data are expressed as the mean ± SD.
Abbreviations: BH, body height; BW, body weight; SBP, systolic blood pressure; DBP, diastolic blood pressure; PR, pulse rate.