Table 3.
Aminoacidic substitutions in isolates exhibiting resistance to flumequine.
| Strain | Aminoacidic Substitution a | |
|---|---|---|
| DNA Gyrase | Topoisomerase IV | |
| Pseudomonas fluorescens 275 | GyrA: S83 by I; GyrB: L417 by H | ParC: Y74 by F; S80 by L; P98 by T |
| Pseudomonas putida FB13 | GyrB: L400 by I; R413 by K; V423 by G | None |
| Rahnella aquatilis FM7 | GyrA: S83 by I; GyrB: L417 by H | ParC: S80 by I |
| Pseudomonas baetica FR34 | GyrB: L417 by H | None |
| Kluyvera intermedia OP29 | GyrA: S83 by I | ParC: S80 by I |
| Pseudomonas putida FB15 | GyrB: L417 by H | None |
| Pseudomonas baetica FE24 | GyrB: L417 by H | None |
| Pseudomonas libanensis FP37 | GyrB: L400 by I; R413 by K; V423 by G | ParC: D101 by N |
| Pseudomonas oryzihabitans FB90 | GyrB: L417 by H | None |
| Pseudomonas sp. FP42 | GyrB: L400 by I; R413 by K | None |
| Pseudomonas sp. 118 | GyrB: L417 by H | None |
| Pseudomonas putida FM4 | GyrB: L400 by I; R413 by K | None |
| Pseudomonas sp. FM15 | GyrB: L400 by I; R413 by K | None |
| Pseudomonas japonica FM22 | GyrB: L400 by I; R413 by K | None |
| Pseudomonas migulae FP68 | GyrB: L400 by I; R413 by K | None |
| Pseudomonas vranovensis FR20 | None | None |
| Pseudomonas azotoformans FR27 | None | None |
a: S, Serine; I, Isoleucine; L, Leucine; H, Histidine, Y, Tyrosine; F, Phenyl-alanine; P, Proline; T, Threonine; R, Arginine; K, Lysine; V, Valine; G, Glycine; D, Aspartic acid; N, Asparagine.