Table 1.
Sham Control | No Treatment | C+P | C+P/NOX Inhibitor | |
---|---|---|---|---|
MAP (mmHg) | ||||
Pre MCAO | 86.6 ± 2.5 | 85.8 ± 2.5 | 86.5 ± 2.9 | 84.2 ± 2.1 |
Onset of reperfusion | 88.6 ± 2.8 | 87.9 ± 2.8 | 86.3 ± 3.6 | 89.1 ± 3.3 |
After reperfusion | 83.2 ± 3.0 | 86.5 ± 2.8 | 84.5 ± 4.4 | 86.2 ± 3.7 |
pO2 (mmHg) | ||||
Pre MCAO | 134.8 ± 5.6 | 135.5 ± 5.0 | 133.6 ± 5.3 | 134.9 ± 5.7 |
Onset of reperfusion | 131.3 ± 6.7 | 132.7 ± 5.8 | 133.1 ± 6.3 | 131.5 ± 6.7 |
After reperfusion | 134.1 ± 8.8 | 140.1 ± 7.3 | 136.9 ± 6.2 | 139.1 ± 7.7 |
pCO2 (mmHg) | ||||
Pre MCAO | 45.0 ± 1.4 | 46.2 ± 1.9 | 46.8 ± 2.9 | 45.5 ± 1.6 |
Onset of reperfusion | 43.6 ± 3.2 | 44.4 ± 2.5 | 43.2 ± 2.7 | 43.9 ± 2.7 |
After reperfusion | 44.6 ± 5.0 | 45.6 ± 2.7 | 46.7 ± 3.3 | 48.1 ± 4.3 |
Sham Control indicates that the control group underwent the entire surgical procedure except for embolization; MAP, mean arterial pressure; MCAO, middle cerebral artery occlusion, C+P, chlorpromazine and promethazine.