Table 2.
The effect of mineralization method on the cell/nanofiber interaction.
| Nanofiber Chemical Composition | Mineralization Method | Cell Type | Cell/Material Interaction | Reference |
|---|---|---|---|---|
| PCL/gelatin, PCL/gelatin/nano–hydroxyapatite (HA) | nano-HA-doped electrospun solution | DPSCs | Cell attachment and growth was not improved | [37] |
| PCL–COOH PCL–COOH-SBF | SBF solution | hASCs | Improved osteogenic differentiation of SBF-treated samples | [38] |
| PLA PLA/Ca3(PO4)2 PLA/Ca3(PO4)2/BSA | SBF-solution, deposition of amorphous Ca3(PO4)2 film | MG-63 | No significant differences for cell adhesion and spreading | [39] |
| PLA/TSF, PLA/TSF/HA | 1.5× SBF doped with 1 wt% of asparaginic acid | MSCs | Improved cell proliferation and differentiation on the PLA/TSF/HA | [14] |
| PLGA, PLGA–COOH, PLGA–COOH-Glu6 | 1.5× SBF | hMSCs | Improved proliferation | [34] |
| PCL/nano–HA PCL/nano–HA–COOH | nano-HAp-doped electrospun solution | MC3T3-E1 | Enhanced attachment, proliferation, and differentiation | [29] |
| PCL, PCL–COOH PCL–COOH/PRP | - | MRC-5 | The number of adhered cells did not differ significantly. More uniform cell distribution on the surface of PCL–COOH | [40] |
| PLGA (control), PLGA/HA PLGA/HA/ Dexamethasone | nano-HA-doped electrospun solution | MC3T3-E1 | Slow cell proliferation compared with control | [41] |
| PLLA/PCL | Electrochemical deposition | rBMSCs | enhanced the osteogenic differen- tiation and proliferation of rBMSCs for treated sample | [17] |
| BR or G-BR nanoparticles into PHBV nanofibers | Electrochemical deposition | hFOB | Enhanced cell proliferation | [42] |
Dental pulp stem cells (DPSCs), human adipose derived stem cells (hASCs), mesenchemal stem cells (MSCs), rate bone MSCs (rBMSCs), human fetal osteoblastic cells (hFOB).