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TAB-DAS-(PEI)NPs increment cycle arrest and cell death more in TAB resistant cells. BT474 and BT474-RH were exposed to free DAS, free TAB, and DAS-loaded formulations at the indicated concentration. (a) Parental and TAB-resistant BT474 cells increment of G0/G1 after 24 h of treatment compared to control. (b) Cell death presented in U.A. relatives of non-treated control cells after 72 h of treatments. * p < 0.05; ** p < 0.01; *** p < 0.001.
