Table 1.
Healthy Smokers n=23 | COPD Smokers n=23 | ||
---|---|---|---|
Female/male | n | 6/17 | 6/17 |
Age | Years | 54 (42, 65) | 55 (46, 68) |
BMI | kg/m2 | 25.4 ± 2.5 | 25.2 ± 3,4 |
Pack-years | 39 ± 23.2 | 47.9 ± 11.0*** | |
FEV1a | L | 3.8 ± 0.8 | 2.2 ± 0.4*** |
FEV1a | % pred | 112.5 ± 14.1 | 66.1 ± 7.2*** |
FEV1 /FVCa | % | 75.4 ± 5.0 | 50.0 ± 8.7*** |
Systolic BP | [mmHg] | 135.7 ± 10.8 | 133.4 ± 17.7 |
Diastolic BP | [mmHg] | 83.2 ± 8.8 | 80.3 ± 9.1 |
WPeak | W | 154.8 ± 35.1 | 110.9 ± 23.9*** |
Notes: Values are presented as mean ± SD, age as median (min, max). ***p<0.001, WPeak, Peak exercise level, which could be maintained for 30 s (during an escalation scheme with a stepwise increase in the work rate by 10 W every minute). aData of COPD patients were assessed post-bronchodilator treatment.
Abbreviations: BMI, body mass index; BP, blood pressure.