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Structural similarity among PF74, PF74-based compounds and host factors.
| PF74 | BI-2 | CPSF6 | NUP153 | GS-CA1 | GS-6207 | Pep-1 |
|---|---|---|---|---|---|---|
| phenyl | phenyl | F321 | F1417 | difluorobenzyl | difluorobenzyl | phenylalanine |
| phenyl | phenol | - | - | Indazole | Indazole | proline |
| indole | - | G318-Q3191 | - | cyclopenta-pyrazole | cyclopenta-pyrazole | valine |
| - | - | F1415 | methanesulfonyl | methanesulfonyl | phenylalanine |
1 A part of G318-Q319 dipeptide of CPSF6 is topologically close to the indole ring of PF74.
