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. 2019 Dec 11;11(1):77–82. doi: 10.1021/acsmedchemlett.9b00499

Figure 3.

Figure 3

Overlay of crystal structures 6GQL (c-KIT, cyan) and 6GQQ (KDR, gold) showing the position of the crystallographic water near the T670 gatekeeper residue of c-KIT and the triazole region of 2 adjacent to the DFG pocket.