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TEM of corneal epithelial–stromal interactions. (A) The presence of secreted collagen and extracellular vesicles were apparent between human corneal epithelial cells (hCECs) and human corneal fibroblasts (hCFs) (dashed box enlarged in right panel). (B) Extracellular vesicles were also present in between hCF cell populations (dashed box enlarged in right panel). Arrowheads = extracellular vesicles; * = mitochondria; † = vacuole; and ‡ = lysosome. Magnification = 12,000×.
