1. Placebo group risk of admission/length of stay.

Study	Placebo group ‐ participants	Placebo group ‐ primary outcomes
OUTPATIENT STUDIES		Risk of admission day 1 (%)	Risk of admission day 7 (%)
Barlas 1998	30	17%	NR
Berger 1998	18	11%	NR
Corneli 2007	295	41%	49%
Goebel 2000	24	8%	21%
Kuyucu 2004	11	0%	0%
Mesquita 2009	32	22%	NR
Plint 2009	201	18%	26%
Schuh 2002	34	44%	47%
INPATIENT STUDIES		Length of stay (mean ± SD days)
Bentur 2005	32	6.3 ± 8.8
Cade 2000	79	2 ± 2.2
De Boeck 1997	15	6.6 ± 1.2
Gomez 2007	25	0.8 ± 0.2
Klassen 1997	32	2 ± 0.7
Richter 1998	19	3 ± 1.6
Teeratakulpisarn 2007	85	2.8 ± 1.7
Zhang 2003	24	5 ± 3.3

NR = not reported
 SD = standard deviation