Table 2.
Univariate and Multivariate cox-regression analyses of prognostic factors for gastric cancer
| Factor | Number | 5-year OS | ||||
|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate regression a | |||||
| Cumulative Rate(%) | OR(95%CI) | P-value | OR(95%CI) | P-value | ||
| Age (≥65:< 65 years) | 24:82 | 34.0:40.5 | 0.948(0.520–1.727) | 0.978 | ||
| BMI (≥25.0:< 25.0 kg/m2) | 13:93 | 35.9:39.5 | 0.916(0416–2.018) | 0.842 | ||
| Gender (Male:Female) | 65:41 | 40.4:37.6 | 1.355(0.807–2.275) | 0.230 | ||
| Blood Type (A:AB:B:O) | 43:10:22:30 | 44.4:15.6:46.4:34.2 | 1.092(0.496–2.405) | 0.936 | ||
| Tumor location (GEJ:Upper:Middle:Lower third) | 5:27:28:46 | 26.7:20.2:46.4:51:1 | 0.988(0.915–1.067) | 0.705 | ||
| Surgical resection (Proximal:Distal:Total) | 13:45:48 | 35.9:46.6:32.4 | 1.143(0.776–1.682) | 0.538 | ||
| TNM stage (I + II:III + IV) | 37:69 | 67.9:23.4 | 3.336(2.205–5.049) | 0.001 | 2.609(1.725–4.194) | < 0.001 |
| Histology (Well:Moderate:Poor) | 7:19:80 | 33.3:46.4:40.3 | 1.154(0.761–1.750) | 0.128 | 1.049(0.653–1.686) | 0.844 |
| IHC C3 score (Low:High)) | 41:65 | 52.6:29.7 | 2.109(1.198–3.714) | 0.005 | 1.848(1.015–3.363) | 0.045 |
| Plasma C3 (Low:Normal) | 40:66 | 22.9:47.2 | 1.730(1.034–2.897) | 0.062 | 1.801(1.049–3.090) | 0.033 |
| CEA (Normal:Elevated) | 81:25 | 48.5:7.4 | 2.673(1.556–4.592) | 0.005 | 1.225(0.680–2.208) | 0.500 |
| Morbidity b (Yes:No) | 59:47 | 72.3:5.2 | 4.799(2.669–8.628) | < 0.001 | 2.770(1.446–5.305) | 0.002 |
aThose factors were qualified from the univariate analysis of overall survival, which their P values were less than 0.20. b Any postoperative complication was considered as morbidity and pooled together for survival comparison. Abbreviations: OS, overall survival; DFS, disease-free survival; OR, odds ratio; CI, confidential intervals; BMI, body mass index; SLRC, SMA-guided laparoscopic right hemicolectomy; CLRC, conventional laparoscopic right hemicolectomy.