Dohn 1968.
Methods | Study design: Randomised by 'drug coding', double blinded, cross‐over trial. Withdrawals post‐randomisation: 2 subjects completed first 12 week period only. |
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Participants | Country: Denmark. No. of patients: 44 randomised. Age: 5 subjects < 50 years, 34 subjects 50 to 69 years, 5 subjects > 70 years. Gender: male. Inclusion criteria: Intermittent claudication, "43 due to arteriosclerosis, 1 due to Buerger's disease'". Exclusion criteria: None mentioned. |
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Interventions | Treatment: 300 mg testosterone isobutyrate (orally), once every 24 days. Control: 50 mg meprobromate. Duration: 12 weeks treatment followed by 12 weeks control or vice versa. |
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Outcomes | Subjective effects, metronome walking test, plethysmography, side effects. | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |