Hentzer 1967.

Methods	Study design: quasi‐randomised by alternation, double‐blind trial. Withdrawals post‐randomisation: 1 drop‐out and 2 deaths not included in analysis.
Participants	Country: Denmark. No. of patients: 39 randomised, 36 completed study. Age: mean 59.4 years experimental group, 63.1 years control group. Gender: male. Inclusion criteria: intermittent claudication, absent peripheral pulses and reduced muscle blood flow. Exclusion criteria: mild symptoms of intermittent claudication only and patients with ulceration.
Interventions	Treatment: 19 patients received 200 mg testosterone (intramuscularly), once weekly for 3 weeks, once every 2 weeks thereafter. Control: 17 patients received 2 ml sesame oil. Duration: 6 months
Outcomes	Subjective effects, walking distance (time to onset of intermittent claudication when stepping), venous filling time, muscle blood flow, side effects
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	High risk	C ‐ Inadequate