NCT00504712.
Methods | Randomised, double blind study. |
Participants | Male, 18 years and older Type 2 diabetes mellitus. Serum testosterone 12 nmol/L or less on two consecutive samples taken on different days and symptoms compatible with hypogonadism. Peripheral vascular disease as defined by previous diagnosis by a specialist vascular surgeon or ABPI less than 0.92 and ischaemic leg pain (claudication or rest pain) or distal complications (non‐healing arterial foot ulcer or gangrene). |
Interventions | Testosterone Sustanon, 200 mg intramuscular testosterone every 2 weeks Placebo 0.9% saline injection every two weeks |
Outcomes | Primary outcome measures: change in arterial stiffness (time frame: 3 months) |
Notes | Author was contacted, not yet published but forms part of MD thesis. |