4. Senna versus lactulose.

Outcome or subgroup	Participants	Effect estimate*
Mean number of defecation days	75	MD ‐0.10; 95% CI ‐0.60 to 0.40
Defecation‐free days	75	MD 0.00; 95% CI ‐0.48 to 0.48
General state of health	75	MD ‐0.10; 95% CI ‐0.31 to 0.11
Overall finding	‐	No difference in laxation response

* If data available and appropriate effect estimate was presented as an odds ratio (OR) or a mean difference (MD) with 95% confidence interval (CI). If not available or appropriate then effect was reported as stated in the trial.