Hansen 1994

Methods	Country: Denmark Setting/Design: Multicentre Time frame: NS Randomisation method: NS Blinding ‐ Participants: Yes ‐ Investigators: Yes ‐ Outcome assessors: No ‐ Data analysis: No Intention‐to‐treat: No Follow‐up period: 24 months Loss to follow‐up: 1
Participants	Inclusion criteria DM: Type 1 (duration 4‐28 years) Onset of diabetes: Before 39 years Age: 18‐55 years BP: < 160/95 mm Hg for patients >35 years and < 145/90 mm Hg < 35 years UAE: 20‐200 µg/min in more than 1 of 3 overnight urines collected during a screening procedure Captopril group Number: 10 Age: 32 (13) Sex (M/F): 9/1 Placebo group Number: 12 Age: 33 (8) Sex (M/F): 9/3 Exclusion criteria Treatment with antihypertensive or diuretic drugs
Interventions	Captopril group 100 mg/d Placebo group Co‐interventions: No
Outcomes	BP UAE Renal clearance Extracellular volume Echocardiography Glycaemic control
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear