Marre 1987

Methods	Country: France Setting/Design: Hospital Time frame: NS Randomisation method: NS Blinding ‐ Participants: Yes ‐ Investigators: Yes ‐ Outcome assessors: No ‐ Data analysis: No Intention‐to‐treat: No Follow‐up period: 6 months Loss to follow‐up: 0
Participants	Inclusion criteria Age: 20‐60 DM: Type I or 2 known for at least five years BMI: <30 kg/ m² AER: 30‐300 mg/24 h in at least 2 of 3 monthly measurements BP: Supine < 160/95 mm Hg on 3 consecutive monthly visits to the outpatient clinic Enalapril group Number: 10 Age: 39.3 (11.6) Sex (M/F): 6/4 Placebo group Number: 10 Age: 38.9 (10.9) Sex (M/F): 6/4 Exclusion criteria Heart, kidney, liver or systemic disease No taking drugs except antidiabetic agent or contraceptives
Interventions	Enalapril group 20 mg/d Placebo group Co‐interventions: No
Outcomes	AER BP GFR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate