Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The metamorphic nature of WT-XCL1 is necessary for potent antimicrobial activity. Restricting XCL1 to its monomeric form (CC3) abolishes antimicrobial activity, while variants with access to the unfolded or alternative dimeric conformations retain activity. XCL1 monomer and dimer structures are represented from PDB ID 1J9O and 2JP1, respectively.
