Hopwood 2008.
Methods | RCT, computer‐generated random number list stratified with BI
C: sequentially numbered, sealed, opaque envelopes
Blinding: outcome assessors
ITT analysis: yes
Numbers of withdrawals: 10 in acupuncture group, 3 in control group Numbers of losses to FU: 2 in acupuncture group, 4 in control group |
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Participants | Country: UK
92 participants (42.8% male, age not reported) with acute ischemic stroke completed treatment. Treatment: 47, control: 45 Between 4 and 10 days from stroke onset 50% CT scan before entry Health conditions before stroke: without previous stroke or TIA, serious comorbidity, cardiac pacemaker Comparability: age, SSS score, and BI similar |
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Interventions | Treatment group: 10 acupoints on paralyzed side, manual (GB20, GB31, GB43, etc.) or electrical stimulation (LI10, SJ5, GB34), 30 minutes/session, 3 times per week for 4 weeks
Control group: placebo acupuncture (deactivated TENS) Both groups: drug therapy, routine physiotherapy, and occupational therapy |
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Outcomes | BI, Motricity Index, NHP at entry, 3, 6, 12, 24, and 52 weeks
Place of residence at 24 and 52 weeks Adverse events |
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Notes | FU: 1 year | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer‐generated random number list stratified with BI |
Allocation concealment (selection bias) | Low risk | Sequentially numbered, sealed, opaque envelopes |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants not blinded to treatment |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Blinding of outcome assessors |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 13 in acupuncture group and 12 in control group lost to follow‐up |
Selective reporting (reporting bias) | Unclear risk | Insufficient information to permit judgement |
Other bias | Unclear risk | Insufficient information to permit judgement |