Table 1.
miRNAs | Regulation | Target Genes | Functions | Ref. |
---|---|---|---|---|
Granulosa cells | ||||
miR-10a;miR-105 | miR-182: | CyclinB1;TdT | Involve in GC | [45] |
miR-23a | Caspase-3 dependent apoptosis pathway | XIAP;Caspase-3 | Pro-apoptotic role | [21] |
miR-21 | COL4A1 | Regulate COL4A1 synthesis | [41] | |
miR-125b | Induced by dihydrotestosterone-1 and testosterone | BAK;BAX | Suppression of proapoptotic | [41] |
Oocytes | ||||
miR-184;miR-10a miR-100 | - | SMARCA5 NCOR2;HOXA1 | Oocyte reprogramming; Repression nuclear receptors; Regulation of oocyte-specific gene expression | [10,27,30,60] |
miR-20a;miR-15a miR-602 | miR-20a, miR-15a: dynamic changes during meiosis | miR-15a: BCL-2 family;CDC25A | Regulation of cell division and cell growth | [33] |
microRNAs in Ovary | ||||
let-7d, let-7e, let-7g has-mir-106b; has-mir-142-3p; has-mir-146a |
[19] |