3. Summary of study characteristics.
|
Ref ID (no. participants) |
Setting | Population | Intervention 1 | Intervention 2 | Treatment duration | Follow‐up | Background Treatment | Notes |
| Topical antiseptics versus placebo/no treatment | ||||||||
|
Minja 2006 (n = 254 people) |
Tanzania, Schools (community) |
Children with CSOM for more than 3 months Mean age 11.8 years |
Boric acid in alcohol ear drops No further information |
No treatment | 1 month | 3 to 4 months | Daily aural toilet (dry mopping) | Cluster‐randomised trial by school Part of a 3‐arm trial |
|
Eason 1986 (n = 43 people) |
Solomon Islands, villages (community) | Children with CSOM for more than 3 months Mean age 5.4 years |
2% boric acid in 20% alcohol 3 ear drops/6 hours |
No treatment | Up to 6 weeks | 4 to 6 weeks | Daily aural toilet (dry mopping) | Part of a 5‐arm trial |
|
Van Hasselt 1998b (n = ? people, 174 ears) |
Malawi, villages (community) |
"CSOM" (no further definition) No age information |
1% povidone Iodine in 1.5% hypromellose (HPMC) – single application | HPMC alone | Single application | 1 week | Suction cleaning before application | Unpublished study Part of 3‐arm trial |
| Topical antiseptic A versus topical antiseptics B | ||||||||
|
Loock 2012 (n = 106 people) |
South Africa, City (secondary care) | Patients with otorrhoea because of active mucosal COM Age over 6 years (90% between 20 and 34 years) |
1% acetic acid 6 drops/12 hours |
Boric acid powder Single administration |
4 weeks (except for boric acid) | Up to 8 weeks | Aural cleaning at 1st visit | Part of a 3‐arm trial |
|
Papastavros 1989 (n = ?, 48 ears) |
Greece, city (secondary care) |
Patients with discharging ears 11 to 79 years |
Hydrogen peroxide, no further information | Borax powder insufflation, no further information | 10 days | 10 days | None | — |