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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: FASEB J. 2019 Dec 2;34(1):1546–1557. doi: 10.1096/fj.201901466R

Figure 2. Pharmacological and nutritional perturbations that increase glucose levels are exacerbated by loss of gpr27.

Figure 2.

A) Relative expression of ins, pck1 and glut2 mRNA in gpr27 wildtype and knockout larvae (n = 11 samples of 10 larvae). B) Glucose levels in 6 d.p.f. larvae generated from heterozygous crosses (n = 20–22 larvae, experiments were replicated at least 3 times). Glucose levels in gpr27 wildtype and knockout larvae treated with C) DMSO or 100 μM hydrocortisone (n = 22–24 larvae, experiments were replicated at least 3 times). Glucose levels in gpr27 wildtype and knockout larvae fed a D) standard diet or a high fat diet (n = 22–24 larvae, experiments were replicated at least 3 times). Statistically significant differences between groups are denoted by lines and asterisks (p < 1E-07). Vertical bars denote the stand deviation and horizontal bars denote the mean.