Figure 5.
Box‐plots of selected 22:6‐ or 20:4‐containing PCs and PEs of WT, Adipor1−/−, and Mfrprd6 mouse RPE‐eyecups. Most of the single 22:6‐containing PC species in the RPE‐eyecups show higher abundance in the mutants, unlike in the retinas. PC(22:6/22:6) or PC(22:6 combined with a VLC‐PUFA) show great reduction in the mutants. 20:4‐containing PE is reduced in the mutants, which is also an opposite observation from the retinas. Single 22:6‐containing PEs are also increased in mutants, but PE (22:6/22:6) shows a great reduction in mutants, similar to the retina. Non‐22:6 or 20:4 containing PE(20:0/22:1) also show great reduction in the mutants