Figure 6.

PCs containing VLC‐PUFAs in Adipor1^−/− and Mfrp^rd6 eyes are greatly reduced. A, Principal component analysis of targeted PCs illustrates tissue‐specific lipid profiles in mutants and WT mice (n = 12). B, C, Hierarchical clustering of significantly differentially occurring PC species (ANOVA one‐way) in Adipor1^−/− and Mfrp^rd6 retinas and RPE‐eyecups compared to WT (P ≤ .05, absolute value fold‐change ≥ 1.5) suggests compensatory PC dynamics. D, Venn diagram illustrates overlap of differentially occurring PCs across strains and tissues