Figure-5.

Differential regulation of a subset of genes by IGF1 signaling in dexamethasone (DEX)-treated C2C12 cells. (A) A Venn diagram summarizing data from the RNA-seq analysis showing the number of differentially regulated genes that were in common between the comparison of untreated C2C12 cells expressing empty vector versus DEX-treated C2C12 cells expressing empty vector (Empty vs Empty DEX) and the comparison of DEX-treated C2C12 cells expressing empty vector versus DEX-treated C2C12 cells expressing ms.sgRNA2 (ms.sgRNA2 DEX vs Empty DEX). (B) A heatmap of the Z-scores for the 33 genes that were identified in (A). Four biological replicates were performed.