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. 2020 Jan 1;10(3):1016–1032. doi: 10.7150/thno.38537

Figure 2.

Figure 2

Lack of catalytically active PTPN13 increases mammary tumor frequency in HER2+ mice. A: Protein domain structure of PTP-BL and PTP-BL△P. B: Kaplan-Meier analysis of tumor occurrence in MMTV-HER2; PTP-BL+/+ (HER2+/BL-wt) and MMTV-HER2; PTP-BL△P/△P (HER2+/BL-ΔP) transgenic female mice. The curves were drawn and analyzed using the Prism software. P value obtained using the log rank test. The number of animals analyzed for each genotype (n) and the median time to tumor onset (T50) are also shown.