Figure 5.

Tumor targeting ability and whole body distribution of MNPs. (A) Mice in vivo images after treatment with CD20-HSPI&Fe₃O₄@SiNPs and HSPI&Fe₃O₄@SiNPs for 0.5, 1, 2, and 24 h (intravenous injection). Most HSPI&Fe₃O₄@SiNPs gathered at the liver, whereas, the CD20-HSPI&Fe₃O₄@SiNPswere primarily concentrated in the tumor region. (B) Ex vivo images of mice after 24 h of treatment with CD20-HSPI&Fe₃O₄@SiNPs and HSPI&Fe₃O₄@SiNPs. (C: control; 1: HSPI&Fe₃O₄@SiNP injection; 2: CD20-HSPI&Fe₃O₄@SiNP injection)