Skip to main content
. 2020 Jan 1;10(3):1415–1432. doi: 10.7150/thno.40857

Figure 7.

Figure 7

Restoring MFN1 expression relieved miR-142a-5p mediated atrophy of denervated gastrocnemius. (A) Gastrocnemius of different groups harvested 2 weeks post-denervation. (B) Western blotting analysis confirmed the expressions of MFN1 and MHC. (C) The wet weight ratio of gastrocnemius in different groups. (D) Morphological observation of gastrocnemius muscles in different groups by HE staining. Scale bar 50 μm. (E, F) Quantification of muscle fibers diameter by immunofluorescence staining of WGA. Scale bar 50 µm. Data were presented as mean ± SD. n=5. *P < 0.05 (vs den). #P < 0.05 vs den + agomir group. Den, denervation; Con, control.