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. 2020 Jan 1;10(3):1136–1150. doi: 10.7150/thno.38287

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(A-B) Proliferation inhibition of PANC02 (A) and H7 (B) tumor cell lines treated with combination of PTX and GEM for 96 h. Combination index (CI) of PTX and GEM was calculated to 0.5 and 0.6 for PANC02 and H7, respectively. (C-D) MTT cytotoxicity assay of PGEM prodrug micelles in PANC02 (C) and H7 (D) cell lines with free GEM as the control. (E-F) MTT cytotoxicity of various formulations in PANC02 (E) and H7 (F) cells. Cells were treated with different micelles for 72 h. All data are reported as means ± SD.