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Characterization of PGEM micelles loaded with PTX at different carrier/drug ratios.
| Micelles | Mass ratio (mg: mg) |
Size (nm)a | PDIb | DLC(%)c | DLE(%)d |
|---|---|---|---|---|---|
| PGEM | -- | 13.14 | 0.169 | ||
| PGEM: PTX | 20: 1 | 13.95 | 0.136 | 4.4 | 93.8 |
| PGEM: PTX | 10: 1 | 14.90 | 0.151 | 8.3 | 91.3 |
| PGEM: PTX | 5: 1 | 17.77 | 0.227 | 14.8 | 88.5 |
| PGEM: PTX | 2.5: 1 | 23.07 | 0.265 | 24.2 | 84.6 |
Notes: aMeasured by dynamic light scattering particle sizer. bPDI = polydispersity index. cDLC = drug loading capacity. dDLE = drug loading efficiency.
