. 2020 Jan 1;10(3):1373–1390. doi: 10.7150/thno.39157

Table 1.

MICs (μg/ml) of the designed peptides against several bacterial strains.

	Microorganisms	MIC (μg/ml)
	Microorganisms	MSI-1	MSI-2	MSI-3	MSI-4	MSI	MSI-78	Penicillin
G^-	E. coli ATCC25922	8	64	4	16	128	16	0.25
	E. coli A2 (ESBLs ⁽⁺⁾)	8	128	8	32	>256	8	>256
	E. coli A5 (ESBLs ⁽⁺⁾)	4	128	4	16	128	16	>256
	E. coli A9 (ESBLs ⁽⁺⁾)	8	64	8	32	64	16	>256
	P. aeruginosa ATCC27853	16	128	16	32	256	16	0.5
	P. aeruginosa T1 (ESBLs ⁽⁺⁾)	16	>256	16	16	>256	32	>256
	P. aeruginosa T6 (ESBLs ⁽⁺⁾)	8	>256	8	32	256	16	>256
	P. aeruginosa T8 (ESBLs ⁽⁺⁾)	16	>256	8	64	>256	16	>256
	K. peneumoniae ATCC4352	4	256	8	32	>256	8	1.0
	K. peneumoniae B4 (ESBLs ⁽⁺⁾)	8	>256	16	64	>256	16	>256
	K. peneumoniae B6 (ESBLs ⁽⁺⁾)	8	128	8	32	128	16	>256
	K. peneumoniae B9 (ESBLs ⁽⁺⁾)	16	>256	8	16	256	32	>256
	E. cloacae S1 (AmpC ⁽⁺⁾)	4	128	4	16	>256	16	>256
	E. cloacae S3 (AmpC ⁽⁺⁾)	8	>256	4	32	128	16	>256
	Shigella flexneri	8	>256	8	16	256	32	>256

G⁺	S. aureus ATCC25923	16	256	8	16	64	16	0.125
	MSSA D1	8	128	4	32	128	16	0.5
	MSSA D4	8	>256	8	16	>256	32	0.125
	MRSA M101	16	>256	16	32	>256	32	>256
	MRSA M108	8	>256	8	64	>256	16	>256
	S. epidermidis ATCC35984	8	128	4	16	128	16	0.5
	MSSE E8	8	256	8	16	128	16	1.0
	MSSE E3	16	>256	8	16	>256	32	2.0
	MRSE N109	16	>256	16	32	>256	16	>256
	MRSE N104	16	>256	16	32	>256	32	>256
	S. pneumoniae ATCC 49619	8	256	8	16	256	16	0.25
	PISP F22	16	>256	16	32	>256	16	1.0
	PISP F34	8	128	8	16	>256	32	0.5
	PRSP P112	32	>256	16	32	128	32	>256
	PRSP P105	16	>256	16	64	>256	16	>256
	E. faecium	4	>256	4	16	>256	8	>256
	E. faecalis	8	>256	8	32	>256	16	>256

MSSA: Methicillin sensitive Staphylococcus aureus; MRSA: Methicillin resistant Staphylococcus aureus; MSSE: Methicillin sensitive Staphylococcus epidermidis; MRSE: Methicillin resistant Staphylococcus epidermidis; PISP: Penicillin international susceptible Streptococcus pneumoniae; PRSP: Penicillin resistant Streptococcus pneumoniae.

Clinical strains with different numbers were isolated from human clinical specimens by the Medical Laboratory Center of Zhongda Hospital (Nanjing, Jiangsu, China).