Figure 1.

Experimental design of bioreactor physical model: Scaffold-cartilage constructs were cultured under unconfined conditions (U), or peripherally confined conditions (C) for 28 days. Constructs were then subjected to either continued static culture (0 N), or a sinusoidal load of 1 N or 6 N, applied at 0.5 Hz once every day for 450 cycles for 5 days per week for 14 days.