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. 2020 Jan 9;16:87–99. doi: 10.2147/NDT.S198772

Table 1.

Thiamine Deficiency Associated Neurological Syndrome

Syndrome, Publication Symptomatology Pathology
Wernicke Encephalopathy - Carl Wernicke, Germany, 188128 Acute onset of ophthalmoplegia, ataxia, and mental confusion14 Hemorrhagic lesions in the mamillary bodies (confusion), hypothalamic nucleus, the periaqueductal region, pons, superior vermis of cerebellum88
Korsakoff´s Syndrome - Sergej Korsakoff, Moscow, 188727 Severe memory loss, anterograde amnesia, confabulation, desorientation8 Lesions in the diencephalon-hippocampal circuit: midline thalamus, anterior thalamic nuclei88
Marchiafava-Bignami-Syndrome - Ettore Marchiafava, Amico Bignami, Rome 191389 Altered mental state, impaired walking, loss of consciousness, dysarthria, pyramidal signs, impaired memory, seizures29 Necrosis and atrophy in the corpus callosum29