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. 2020 Jan 9;13:243–252. doi: 10.2147/OTT.S232405

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© 2020 Wang et al.

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PVT1 enhances OSCC cell proliferation and cisplatin resistance. (A) Effect of pcDNA-PVT1 on PVT1 level in SCC9-R and CAL27-R cells. (B) Effect of si-PVT1 on PVT1 level in SCC9-R and CAL27-R cells. (C and D) Cell survival rate of SCC9-R (C) and CAL27-R (D) cells transfected with pcDNA-NC, pcDNA-PVT1, si-NC or si-PVT1 simultaneously under cisplatin pressure examined with CCK-8 assay. (E and F) Colony formation ability of SCC9-R (E) and CAL27-R (F) cells transfected with pcDNA-NC, pcDNA-PVT1, si-NC or si-PVT1 simultaneously under cisplatin pressure examined with colony formation assay. (G and H) Cell proliferation ability of SCC9-R (G) and CAL27-R (H) cells transfected with pcDNA-NC, pcDNA-PVT1, si-NC or si-PVT1 simultaneously under cisplatin pressure examined with CCK-8 assay. *P<0.05, **P<0.01.