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. 2019 Dec 18;127(12):127006. doi: 10.1289/EHP5139

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EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. All content is public domain unless otherwise noted.

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Figure 6 comprises a Western blotting for H1F 1 alpha (120 kilo Dalton), GLUT 1 (55 kilo Dalton), EPO (21 kilo Dalton), VEGF A (17 kilo Dalton), and beta actin (43 kilo Dalton), as well as a bar graph with standard deviation plotting relative protein expression per beta actin (y-axis) across treatment with 0, 2, 4, 6, 8, and 10 of methylmercury (milligrams per kilogram) (x-axis). — Protein expression of $HIF- 1 α$ and downstream effectors following MeHg administration in in vivo rat models. Adult Sprague-Dawley rats were administered with MeHg (0, 2, 4, 6, 8, $10 mg / kg$ ) by intraperitoneal injection for $0.5 h$ . Whole brain lysates were analyzed by Western blotting for the indicated proteins. Note: Data are presented as $mean \pm SD$ ( $n = 6 rats / group$ ). con, control (intraperitoneal injection of saline); EPO, erythropoietin; GLUT-1, glucose transporter 1; $HIF- 1 α$ , Hypoxia-inducible $factor- 1 α$ ; MeHg, methylmercury; VEGF-A, vascular endothelial growth factor A. * $p < 0.05$ vs. control group by one-way ANOVA with Dunnett’s post hoc test.