Fig 2. Association between rs1078761 genotype and BPIFA1 levels in the saliva of clinically stable patients with CF.

The y axis shows P values in the–log₁₀ scale for polymorphisms that were tested for association in the meta-analysis of 6365 CF patients for lung disease severity. rs1078761 remained the most significant association in the region (purple diamond). The extent of linkage disequilibrium (measured by the r² statistic) with rs1078761 for the remaining SNPs is indicated with colors.