Fig. 6.
Inactivation of NaV1.8 currents in rat superior cervical ganglion (SCG) neurons. A: family of wild-type NaV1.8 current traces recorded from an SCG neuron using the inactivation protocol (inset). B: NaV1.8 A1073 current traces acquired using the voltage protocol in A. C: superimposed inactivation curves for both groups of neurons. Solid lines represent the best fit of a modified Boltzmann equation. Data were normalized to the fitted maximum current. D: summary dot plot of the mean (±SE) current density of SCG neurons expressing wild type (n = 21) or NaV1.8 A1073V (n = 15). VH, half-inactivation potential.