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Role of Na+ in pyridoxine uptake by pancreatic acinar cells (PAC) 266-6. Cells were incubated in Krebs-Ringer buffer (pH 7.4) in the presence of Na+ and after its isoosmotic replacement with mannitol or choline. Initial rate (total) of [3H]pyridoxine (7.5 nM) uptake was then determined (30 min, 37°C). Data are means ± SE of 8 separate uptake determinations.
