Table 4.
Normalized brain volume and brain volume calculated with SIENAX in the AD dataset. From left to right, the table lists median [1st and 3rd quartiles] for volumes; Bonferroni-corrected p values for the pairwise comparison of volumes from FFR-processed and full images; volume differences between the full and FFR-processed images as mL and % differences (median [1st and 3rd quartiles]); and ICC (absolute agreement (lower-upper band of 95% CI)) between volumes from full and FFR-processed images
| AD n = (110) | Normalized brain volume | Brain volume | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Volume (L) | p value | Difference | ICC (lower-upper) | Volume (L) | p value | Difference | ICC (lower-upper) | |||
| mL | % | Ml | % | |||||||
| Full |
1.39 [1.34; 1.44] |
1.09 [1.01; 1.16] |
||||||||
| QuickShear |
1.39 [1.35; 1.44] |
0.266 |
1.26 [− 4.40; 8.62] |
0.09 [− 0.32; 0.64] |
0.835 (0.767–0.884) |
1.09 [1.01; 1.16] |
0.001 |
− 2.44 [− 5.11; − 1.22] |
− 025 [− 0.48; − 0.11] |
0.982 (0.982–0.993) |
| FaceMasking |
1.40 [1.35; 1.46] |
0.003 |
5.91 [− 1.57; 16.38] |
0.44 [− 0.12; 1.19] |
0.896 (0.842–0.931) |
1.09 [1.01; 1.16] |
0.392 |
− 0.52 [− 2.47; 1.10] |
− 0.05 [− 0.2; 0.10] |
0.973 (0.960–0.981) |
| Defacing |
1.39 [1.35; 1.44] |
1.000 |
− 2.17 [− 10.80; 7.81] |
− 0.16 [− 0.80; 0.55] |
0.715 (0.610–0.795) |
1.07 [0.99; 1.14] |
< 0.001 |
− 7.60 [− 12.13; − 4.71] |
− 0.69 [− 1.14; 0.43] |
0.933 (0.8.74–0.961) |
Only the images for which FFR was successful and for which the segmentation was successful are included
ICC, intra-class correlation coefficient; n, number of subjects; AD, Alzheimer’s disease