Table 3.
Patient characteristics at ICU admission, based on the presence of ventilator-associated events
| VAC, n = 227 | No VAC, n = 832 | p | IVAC, n = 123 | No IVAC, n = 936 | p | pVAP, n = 62 | No pVAP, n = 997 | p | |
|---|---|---|---|---|---|---|---|---|---|
| Male gender | 164 (72.2) | 531 (63.8) | 0.020 | 88 (71.5) | 607 (64,9) | 0.150 | 44 (71) | 651 (65.3) | 0.372 |
| Age, years | 59 (47–67) | 61 (47–70) | 0.227 | 58 (46–67) | 61 (47–69.7) | 0.121 | 55 (45–66) | 61 (47–70) | 0.006 |
| SAPS II | 56 (46–74) | 59 (46–70) | 0.804 | 58 (44–72) | 58 (46–70) | 0.353 | 60 (47–73) | 58 (46–71) | 0.192 |
| SOFA | 9 (7–12) | 9 (6–11) | 0.041 | 9 (6–12) | 10 (6.25–11) | 0.009 | 9 (7–13) | 9 (7–12) | 0.392 |
| Reason for admission | |||||||||
| Medical vs surgical | 189 (83.3) | 693 (83.3) | 0.933 | 94 (76.4) | 788 (84.2) | 0.026 | 46 (74.2) | 836 (83,9) | 0.043 |
| Septic shock | 65 (28.6) | 200 (24) | 0.162 | 32 (26) | 233 (24.9) | 0.797 | 14 (22.6) | 251 (25.1) | 0.641 |
| Acute respiratory failure | 93 (41) | 282 (33,9) | 0.051 | 43 (35) | 332 (35.5) | 0.898 | 18 (29) | 357 (35.8) | 0.274 |
| Neurologic failure | 39 (17.2) | 171 (20.6) | 0.252 | 21 (17.1) | 189 (20.2) | 0.409 | 11 (17.7) | 199 (20) | 0.665 |
| Soft tissue infection | 23 (10.1) | 83 (10) | 0.953 | 16 (13) | 90 (9.6) | 0.242 | 8 (12.9) | 98 (9.8) | 0.437 |
| Cardiac arrest | 21 (9.3) | 98 (11.8) | 0278 | 13 (10.1) | 106 (11.3) | 0.794 | 9 (14.5) | 110 (11.1) | 0.405 |
| Poisoning | 7 (3.1) | 40 (4.8) | 0.261 | 4 (3.3) | 43 (4.6) | 0.343 | 2 (3.2) | 45 (4.5) | 0.631 |
| Other | 44 (19.4) | 118 (14.2) | 0.056 | 28 (22.8) | 134 (14.3) | 0.015 | 12 (19.4) | 150 (15.1) | 0.364 |
| Charlson comorbidity index | 3 (2–5) | 4 (1–5) | 0.440 | 3 (1–5) | 4 (2–5) | 0.639 | 3 (2–5) | 4 (1–5) | 0.024 |
| Diabetes | 58 (25.6) | 182 (21.9) | 0.248 | 33 (26.8) | 207 (22.2) | 0.246 | 13 (21) | 227 (22.8) | 0.736 |
| Chronic renal failure | 17 (7.5) | 88 (10.6) | 0.899 | 9 (7.3) | 96 (10.3) | 0.302 | 3 (4.8) | 102 (10.3) | 0.167 |
| Chronic heart failure | 40 (17.6) | 150 (18.1) | 0.875 | 22 (17.9) | 168 (18) | 0.978 | 10 (16.1) | 180 (18.1) | 0.696 |
| Chronic respiratory failure | 36 (15.9) | 120 (14.5) | 0.598 | 19 (15.4) | 137 (14.7) | 0.819 | 10 (16.1) | 146 (14.7) | 0.754 |
| Cirrhosis | 23 (10.1) | 70 (8.4) | 0.436 | 13 (10.6) | 80 (8.6) | 0.470 | 6 (9.7) | 87 (8.7) | 0.809 |
| Immunosuppression | 55 (24.2) | 236 (28.4) | 0.209 | 33 (26.8) | 258 (27.6) | 0.853 | 17 (27.4) | 274 (27.5) | 0.984 |
| Obesity | |||||||||
| BMI > 30 | 64 (28.2) | 153 (18.4) | 0.001 | 35 (28.5) | 182 (19.5) | 0.021 | 8 (29) | 199 (20) | 0.088 |
| BMI > 35 | 30 (13.2) | 86 (10.3) | 0.223 | 18 (14.6) | 98 (10.5) | 0.167 | 10 (16.1) | 106 (10.6) | 0.181 |
Data are numbers (%), or median (interquartile range)
BMI, body mass index; SAPS: simplified acute physiology score; SOFA, sepsis-related organ failure assessment