Fig. 1. ESCRT-III accumulation in plasma membrane during ferroptosis.
(A) PANC1 cells were treated with erastin or RSL3 in the absence or presence of indicated cell death inhibitor for 12 h and cell death was assayed (n = 3, *P < 0.05). (B) Western blot analysis of indicated protein expression in isolated plasma membrane in PANC cells following treatment with erastin (10 μM) or RSL3 (0.5 μM) for 12 h. (C) Heat map of protein expression in isolated plasma membrane in PANC cells following treatment with erastin (10 μM) or RSL3 (0.5 μM) for 12 h.
